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Visual Function Tests in Age-Related Macular Degeneration

January 17, 2020


This study is looking to assess visual function tests in people with non-exudative age-related macular degeneration (AMD) – the leading cause of visual impairment in the elderly of developed countries. There are no current approved treatments for dry AMD (the most common type of AMD) and this study hopes to develop research into different stages of the disease and possible treatments.


Study Information

In this study, researchers are looking for 200 participants in four different groups: a normal population, early dry AMD population, intermediate dry AMD population, and advanced dry AMD population. Each of the four groups will undergo a battery of vision tests including dark adaptation, reading tests, color vision function, and shape discrimination.


Inclusion Criteria


All Subjects Must:


  • Be 60 years of age or older
  • Provide written informed consent
  • Be willing and able to follow all instructions and attend the study visits
  • Be able to perform all study procedures


Normal Subjects:


  • Have BCVA of 20/25 or better in the study eye
  • Have no history or clinical evidence of AMD, retinal diseases or any other ocular pathologies in either eye


AMD Subjects:


  • Have BCVA of 20/40 or better in the study eye
  • Have a clinical diagnosis of non-exudative AMD in the study eye


Exclusion Criteria


All subjects must not have any of the below criteria


  • Have a diagnosis of wet AMD in the study eye
  • Have any other hereditary or acquired retinal diseases in either eye
  • Have glaucoma or other optic nerve diseases in either eye
  • Have corneal or other anterior segment diseases in either eye
  • Have significant cataract in the study eye
  • Have a history of ocular trauma or ocular surgery (other than cataract removal) in the study eye
  • Have a history of uncontrolled systemic disease (e.g. poorly controlled hypertension or poorly controlled diabetes)
  • Have a history of seizures
  • On psychotropic medications
  • Any other symptoms or conditions that could, in the opinion of the investigator, interfere with study procedures.



Andover Eye Associates

Andover, Massachusetts, United States, 01810

Principal Investigator: Jason Chin, OD



ORA, Inc.

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